اثر درمانی آلپروستادیل بر زخم انگشتان در مبتلایان به اسکلرودرمی: گزارش موردی از یک درمان جدید

 ABSTRACT Systemic sclerosis is a disease with skin tightness. Besides of skin involvement, there may be involvement of different organs. Systemic sclerosis may be diffuse or limited, but in both of them Raynoud’s phenomen is common. This phenomen is due to vasoconstriction and vascular insufficiency and is a phenomen that makes problem for the patient and does not have any efficient treatment. One of the new drugs under research is Alprostadil, a prostaglandin El analoge. In this report, a case of systemic sclerosis with ulcer on the tip of fingers who has received new treatment, are introduced and discussed.